[3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid

[3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid - Names and Identifiers

Name	[3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid
Synonyms	N-METHYL 4-BORONO-2-FLUOROBENZAMIDE 4-Borono-2-fluoro-N-methylbenzamide 3-Fluoro-4-(methylcarbamoyl)benzeneboronic 3-Fluoro-4-methylcarbamoylphenylboronic acid 3-FLUORO-4-(METHYLCARBAMOYL)BENZENEBORONIC ACID [3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid [3-FLUORO-4-(METHYLCARBAMOYL)PHENYL]BORONIC ACID Boronic acid, B-[3-fluoro-4-[(methylamino)carbonyl]phenyl]-
CAS	849833-86-9
InChI	InChI=1/C8H9BFNO3/c1-11-8(12)6-3-2-5(9(13)14)4-7(6)10/h2-4,13-14H,1H3,(H,11,12)

[3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid - Physico-chemical Properties

Molecular Formula	C8H9BFNO3
Molar Mass	196.97
Density	1.31±0.1 g/cm3(Predicted)
Melting Point	173-175
pKa	7.24±0.18(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.533

[3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant/Keep Cold

[3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid - Introduction

[3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid is an organic compound with the chemical formula C8H9BFNO3.

Nature:
-Appearance is colorless to yellowish solid.
-The melting point is about 125-128°C.
-Slightly soluble in water, low solubility.

Use:
- [3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid is an important organic synthesis intermediate, commonly used in the preparation of drugs and pesticides.
-It can be used as an effective source of fluorobenzamide to introduce fluorine into organic molecules.
-It can also be used to synthesize complexes containing aryl boronic acid esters, and is commonly used in the preparation of various crosslinking reagents, fluorescent probes and catalysts.

Preparation Method:
[3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid is mainly prepared by organic synthesis methods, generally obtained by the reaction of phenylboronic acid and 3-fluoro-4-formanilide.

Safety Information:
- [3-fluoro-4-(methylcarbamoyl)phenyl]boronic acid has low toxicity and irritation, it is still necessary to follow laboratory safety procedures and avoid contact with skin, eyes and respiratory tract.
-During operation, care should be taken to prevent inhalation of dust, and chemically compatible gloves, glasses and protective masks should be used for protection.
-Should be stored in a dry, well-ventilated place, away from heat sources and oxidants.

Last Update：2024-04-09 02:00:48